They all try to do something new and take the risk to be seen as a fool.
Over the last few days I stumbled over three videos by a physicist, an entrepreneur and an actor, which at first have little in common, but they do. They all need to know when they are wrong in order to progress. If you are not wrong, then you are likely to be right, but that is often difficult to prove - often not at all.
I was trained as a mathematician and it was only last year, when I attended the Royal Statistical Society conference and met many statisticians that I understood how different the two groups are.
In mathematics you often start with some axioms, things you assume to be true, and these axioms are then the basis from which new theory is derived. In statistics or more general in science you start with a theory, or better a hypothesis and try to disprove it.